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Breast Cancer · Patient Guide

Breast Cancer — Types, Symptoms & When to See a Specialist

Breast cancer is the most common cancer in Indian women — and one of the most curable when caught early. Survival rates for Stage I breast cancer in modern Indian centres now exceed 95%. Yet the average Indian woman is still diagnosed at a more advanced stage than her counterpart in many Western countries, largely because regular breast self-examination, clinical breast examination, and screening mammography are not yet routine. Understanding the early warning signs, knowing your individual risk, and acting promptly on any change can shift outcomes dramatically.

  • Most common cancer in Indian women — and one of the most curable when caught early
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Patient Guide

What is Breast Cancer?

Breast cancer occurs when cells in the breast — most often in the ducts that carry milk to the nipple, or in the milk-producing lobules — grow uncontrollably and form a tumour. Most breast cancers begin as a small, painless lump that grows slowly over months or years. Some begin as a pre-invasive cancer (called ductal carcinoma in situ, or DCIS) confined to the duct, which over time can progress to invasive cancer that grows into surrounding breast tissue and, eventually, beyond the breast.

Breast cancer is the most common cancer in women worldwide and the most common cancer in urban Indian women. It is also one of the most successfully treated cancers when caught early — modern treatment combines surgery (often breast-conserving rather than full mastectomy), radiation, chemotherapy, targeted therapy, hormonal therapy and immunotherapy, tailored to each tumour's biology. Men can also develop breast cancer, though it is rare and accounts for less than 1% of all cases. Outcomes today depend more on stage at diagnosis and tumour biology than on the patient's age or family history alone — which is why early detection through self-examination, clinical examination and screening mammography matters so much.

Cell type & molecular subtype

Types of Breast Cancer

Breast cancers are classified in two complementary ways — by the cell type from which the cancer arises, and by the molecular receptors it expresses. Both classifications matter for treatment.

Invasive Ductal Carcinoma (IDC)

The most common type, accounting for around 70–80% of breast cancers. IDC begins in the milk ducts and breaks through the duct wall to grow into the surrounding breast tissue. Treatment usually combines surgery (lumpectomy or mastectomy), radiation, and systemic therapy guided by molecular receptor status.

Invasive Lobular Carcinoma (ILC)

Accounts for around 10–15% of breast cancers. ILC begins in the milk-producing lobules and tends to grow in a sheet-like pattern that can be harder to feel as a distinct lump and harder to see on mammograms. Treatment principles are similar to IDC but the surgical approach may need to be more cautious.

Ductal Carcinoma In Situ (DCIS)

Pre-invasive breast cancer confined to the milk ducts and not yet invading surrounding tissue. DCIS is typically detected by screening mammography rather than as a felt lump. Treatment is usually surgery (often breast-conserving) sometimes followed by radiation, with cure rates above 95%.

Triple-Negative Breast Cancer (TNBC)

A molecular subtype rather than a tissue type — defined by tumours that lack oestrogen receptors, progesterone receptors and HER2. TNBC tends to occur in younger women and to grow more aggressively, but is highly responsive to chemotherapy. Modern immunotherapy and PARP inhibitor combinations have meaningfully improved outcomes.

HER2-Positive Breast Cancer

A molecular subtype defined by over-expression of the HER2 protein. Once considered the most aggressive form of breast cancer, HER2-positive disease is now one of the most treatable thanks to HER2-targeted therapies (trastuzumab, pertuzumab, T-DM1, T-DXd). Cure rates for HER2-positive early breast cancer now match or exceed those of other types.

Hormone Receptor-Positive Breast Cancer

Tumours that express oestrogen and/or progesterone receptors — the most common molecular subtype, accounting for around 70% of breast cancers. These cancers respond to hormonal therapy (tamoxifen, aromatase inhibitors, fulvestrant, CDK4/6 inhibitors), which can dramatically reduce recurrence even after surgery.

Inflammatory Breast Cancer

A rare but aggressive form of breast cancer that presents with rapid swelling, redness, warmth and an orange-peel appearance of the breast skin — often without a distinct lump. Easily mistaken for an infection (mastitis). Requires urgent specialist evaluation and intensive multimodal treatment.

Male Breast Cancer

Rare, accounting for less than 1% of all breast cancers. Usually presents as a painless lump behind the nipple in older men, sometimes with nipple retraction or discharge. Treated with similar principles to female breast cancer, with hormonal therapy particularly important since most male breast cancers are hormone receptor-positive.

For detailed information on diagnosis, breast-conserving surgery and oncoplastic options, sentinel lymph node biopsy, modern radiation therapy, targeted therapy and personalised systemic therapy, see our dedicated page on breast cancer treatment in Hyderabad.

Early warning signs

Common Signs & Symptoms of Breast Cancer

Most breast cancers begin as a painless lump, but several other early signs are equally important. Watch for any of the following:

  • A new lump or thickening in the breast or armpit
  • A change in the size, shape or contour of one breast
  • Skin changes over the breast — dimpling, puckering, redness, warmth, or an 'orange-peel' appearance
  • Changes in the nipple — recent inward retraction, scaling or eczema-like skin, or persistent crusting
  • Discharge from one nipple, especially if blood-stained or clear-and-watery
  • Persistent pain or tenderness in one area of the breast (less common as a first sign)
  • A lump under the arm that does not settle
  • An ulcer or non-healing wound on the breast skin
  • Unexplained weight loss, persistent back or bone pain (in advanced disease)
Indian context

Breast Cancer in Telangana & Andhra Pradesh

Breast cancer is now the most common cancer in women across urban Telangana and Andhra Pradesh — and incidence is rising steadily, driven by urbanisation, delayed childbearing, falling rates of prolonged breastfeeding, and rising obesity. A particular Indian pattern matters: breast cancer in Indian women tends to occur about a decade earlier than in Western women, with a meaningful share of cases in women under 40.

Despite this, screening mammography remains underused, and most women are still diagnosed only when they notice a lump themselves — often after months of monitoring. The single most useful step in this region is straightforward: any woman over 40 should have a clinical breast examination annually and a screening mammogram every 1 to 2 years, and any woman with a strong family history should consider genetic counselling and BRCA testing, with mammography starting earlier. Aarogyasri coverage for eligible families and EMI options make modern breast cancer treatment accessible.

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Meet the Specialists

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Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Why it happens

Common Causes & Risk Factors

Breast cancer typically develops from a combination of inherited, hormonal, and lifestyle factors. Established risk factors include:

  • Female sex
  • Increasing age (most breast cancers occur after the age of 40)
  • A personal history of breast cancer or certain benign breast conditions (atypical hyperplasia, lobular carcinoma in situ)
  • Family history of breast or ovarian cancer in a first-degree relative
  • Inherited mutations in BRCA1, BRCA2 or other breast cancer susceptibility genes (PALB2, TP53, CHEK2, ATM, PTEN)
  • Early onset of periods (before age 12) or late menopause (after age 55)
  • Never having been pregnant, or first pregnancy after age 30
  • Not breastfeeding, or breastfeeding for short durations only
  • Long-term hormone replacement therapy after menopause
  • Long-term use of certain oral contraceptive pills (small increase in risk)
  • Previous radiation therapy to the chest (especially before age 30)
  • Obesity, particularly after menopause
  • Heavy alcohol consumption
  • Physical inactivity
  • Dense breast tissue on mammography
Red flags

When to See a Breast Cancer Specialist

Any of the following should prompt a clinical breast examination and, when needed, mammography or breast ultrasound — without further self-monitoring:

  • A new lump or thickening felt in the breast or armpit
  • A change in the size, shape, or feel of one breast
  • Any new skin or nipple change — dimpling, puckering, redness, retraction, scaling, or discharge
  • Blood-stained or clear-and-watery nipple discharge from one breast
  • A breast that becomes red, swollen or warm without an obvious infection (especially if not breastfeeding)
  • An ulcer or non-healing wound on the breast skin
  • An abnormal screening mammogram or breast ultrasound
  • A first-degree relative with breast or ovarian cancer, especially diagnosed at a young age (consider BRCA testing)

A short specialist consultation and the right diagnostic test — imaging, biopsy, or blood test as appropriate — is usually enough to confirm or rule out cancer. Early action is always easier than catching up later.

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Where to get care

Specialist Breast Cancer Care at CION Cancer Clinics

Our NABH-accredited centres across Hyderabad deliver evidence-based breast cancer care — from clinical breast examination, mammography, ultrasound and MRI through to image-guided core-needle biopsy, breast-conserving surgery (lumpectomy with oncoplastic reconstruction), modified radical mastectomy with immediate or delayed reconstruction, sentinel lymph node biopsy, advanced radiation therapy (IMRT/IGRT/partial breast irradiation), chemotherapy, hormonal therapy, HER2-targeted therapy, CDK4/6 inhibitors, immunotherapy and PARP inhibitors for eligible patients — guided by NCCN and ESMO protocols and reviewed for every patient by a multidisciplinary breast tumour board.

For a detailed walk-through of breast cancer diagnosis, treatment options, costs, and our specialist team, see our dedicated page on breast cancer treatment in Hyderabad.

Disclaimer: This page is intended for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified oncologist for guidance specific to your medical condition. Content on this page is periodically reviewed and updated by CION's medical team in accordance with current clinical guidelines.
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Common questions

Breast Cancer — Frequently Asked Questions

What is the first sign of breast cancer?

The most common first sign is a new painless lump or thickening in the breast or armpit. Other early signs include a change in the size, shape or contour of one breast, skin changes over the breast (dimpling, puckering, redness, an orange-peel appearance), nipple changes (recent inward retraction, scaling, persistent crusting), and discharge from one nipple — especially if blood-stained or clear-and-watery. Pain is not usually an early sign of breast cancer, but any persistent unexplained breast pain in one area also deserves evaluation. Any new or changing breast finding deserves a clinical examination — not further self-monitoring.

Are all breast lumps cancer?

No — the great majority of breast lumps are benign. Fibroadenomas (smooth, mobile lumps common in younger women), simple cysts, fibrocystic changes and benign breast disease together account for most breast lumps, especially in women under 35. However, distinguishing benign from cancerous lumps cannot be done reliably by feel alone — it requires a clinical examination combined with imaging (ultrasound for younger women, mammography for women over 35–40) and, when needed, a core-needle biopsy. The combination of these three steps — clinical examination, imaging and biopsy when needed — is called triple assessment and gives a definitive answer in nearly all cases.

Should I get a mammogram? At what age?

Most current guidelines recommend annual or biennial screening mammography for women aged 40–74 at average risk. Women with a strong family history of breast or ovarian cancer, a known BRCA1 or BRCA2 mutation, or previous chest radiation may need to start earlier — sometimes from age 25–30 — and may benefit from breast MRI in addition to mammography. Women with dense breasts may benefit from supplemental ultrasound. Women over 75 should discuss continued screening with their doctor based on overall health. A specialist breast clinic can advise on the right screening schedule for your individual risk.

Is breast cancer curable?

Yes — breast cancer is highly curable when caught early. Stage I breast cancer has 5-year survival rates above 95%, and many patients with early-stage hormone-receptor-positive or HER2-positive disease are cured outright with modern treatment. Even locally advanced (Stage III) breast cancer is cured in a substantial proportion of patients with combined chemotherapy, surgery, radiation and targeted or hormonal therapy. Advanced (Stage IV) breast cancer is not usually curable but can often be controlled for many years with modern systemic therapy, with patients living active lives.

Should I get tested for BRCA gene mutations?

BRCA1 and BRCA2 testing is recommended for women with a strong family history of breast cancer or ovarian cancer — particularly if a first-degree relative was diagnosed before age 50, if multiple relatives are affected, if breast and ovarian cancers occur in the same family, if a male relative had breast cancer, or if the family is of Ashkenazi Jewish background. BRCA testing is also recommended for women diagnosed with breast cancer before 50, triple-negative breast cancer at any age, bilateral breast cancer, or both breast and ovarian cancer. Genetic counselling before testing is essential — it ensures the right person in the family is tested first and that results are interpreted in context. BRCA testing is now available across Hyderabad.

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