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Lung Cancer Care in Hyderabad

Lung Cancer — Types, Symptoms & When to See a Specialist

Lung cancer is the most common cancer death in Indian men — and one of the most rapidly rising cancers in Indian women, including women who have never smoked. Knowing the warning signs, understanding the role of indoor air pollution and second-hand smoke, and acting on a persistent cough or new breathlessness can mean the difference between a curable cancer and one diagnosed too late.

  • Rising in non-smokers — a growing share of cases occur in never-smokers, especially Indian women
  • NSCLC vs SCLC — two very different cancers, two very different treatment paths
  • Curable when caught early — Stage I NSCLC has 70–90% 5-year survival with surgery
  • Molecular testing for every patient — EGFR, ALK, ROS1, KRAS targeted therapy
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Lung Cancer Overview

What is Lung Cancer?

Lung cancer occurs when cells in the lungs or the airways leading into them grow uncontrollably and form a tumour. The lungs sit deep within the chest, well protected by the ribs and the chest wall — which is part of why lung cancer often produces no symptoms until it is locally advanced. Most lung cancers begin in the cells lining the airways (the bronchi) or the small air sacs (alveoli), and they may grow silently for months before producing a persistent cough, a change in voice, breathlessness, or other warning signs.

Lung cancer is divided into two broad groups — non-small cell lung cancer (NSCLC), which accounts for around 85% of cases, and small cell lung cancer (SCLC), which accounts for the remaining 15%. The two are treated very differently. NSCLC includes several subtypes, the most common of which is adenocarcinoma — increasingly seen in non-smokers, particularly Indian women. The good news is that lung cancer treatment has been transformed over the past decade by molecular testing for targetable mutations (EGFR, ALK, ROS1, KRAS), modern immunotherapy and advanced surgical and radiation techniques. When found early, lung cancer is highly curable.

Cell Types & Subtypes

Types of Lung Cancer

Lung cancers are grouped by the cell type they arise from. The distinction matters enormously because treatment, response rates and prognosis differ widely.

≈ 40% of cases

Adenocarcinoma

The most common type of lung cancer overall — and the most common lung cancer in non-smokers, especially women. Often arises in the outer parts of the lung and grows more slowly than other types. Modern treatment relies heavily on molecular testing — many tumours carry targetable mutations (EGFR, ALK, ROS1, BRAF, KRAS, MET) that respond to specific oral targeted therapy, sometimes for years.

≈ 25–30% of cases

Squamous Cell Carcinoma

More strongly linked to smoking than adenocarcinoma. Tends to arise in the central airways and may cause haemoptysis (coughing up blood), persistent cough, or recurrent chest infections relatively early. Treated with a combination of surgery, radiation, chemotherapy and immunotherapy depending on stage.

Less common

Large Cell Lung Cancer

A less common, more aggressive subtype of NSCLC. Treated with similar principles to other NSCLC types but tends to require more intensive systemic therapy.

≈ 15% of cases

Small Cell Lung Cancer (SCLC)

Strongly linked to smoking. SCLC grows and spreads very rapidly — but is also highly responsive to chemotherapy and immunotherapy. Treatment is primarily systemic (chemotherapy combined with immunotherapy and radiation), with surgery reserved for the rare very early-stage cases.

Rare subtypes

Other Lung Cancers

Includes carcinoid tumours (slow-growing neuroendocrine tumours of the lung), pleural mesothelioma (a rare cancer of the lung lining linked to asbestos exposure), and sarcomas of the lung. Each requires a tailored specialist treatment plan.

For detailed information on diagnosis, molecular testing, minimally invasive lung surgery (VATS/RATS), advanced radiation therapy (SBRT), modern targeted therapy and immunotherapy options, see our dedicated page on lung cancer treatment in Hyderabad.

!

Did you know?

A growing share of new lung cancer cases now occur in people who have never smoked. Indian and East Asian women are especially affected — often by adenocarcinoma carrying targetable mutations such as EGFR or ALK. The traditional image of lung cancer as a smoker's disease has become dangerously incomplete.

Warning Signs

Common Signs & Symptoms of Lung Cancer

Lung cancer often produces no symptoms in its early stages. When symptoms do appear, the most important early signs are:

  • A persistent cough lasting more than 3 weeks, or a change in the character of a chronic cough
  • Coughing up blood or blood-stained sputum (haemoptysis)
  • Persistent chest pain, especially with breathing or coughing
  • Shortness of breath that has built up over weeks
  • Recurrent chest infections that take longer than usual to clear
  • Hoarseness of voice that does not settle in 2–3 weeks
  • Unexplained weight loss and loss of appetite
  • Persistent fatigue
  • Difficulty swallowing if the cancer presses on the food pipe
  • Bone pain (suggests spread to bones)
  • Persistent headache, vision changes, or new seizures (suggests spread to the brain)
  • Swelling of the face, neck or arm (a rare sign of pressure on a large chest vein)

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Meet the Specialists

17+ senior cancer specialists. One panel for your case.

Trained at AIIMS, Tata Memorial, and leading international centres. Combined 150+ years of experience. Every complex case is reviewed by 3+ of them — together.

Dr. Naresh Gundu
Medical Oncologist

Dr. Naresh Gundu

MBBS, DNB (Internal Medicine), DM (Medical Oncology)

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Dr. C. Raghavendra Reddy
Medical Oncologist

Dr. C. Raghavendra Reddy

MBBS(Gold Medal), DNB(General Medicine), DM(Medical Oncology)(Gold Medal)

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Dr. Bharati Devi Gorantla
Medical Oncologist

Dr. Bharati Devi Gorantla

MBBS, MD(General Medicine), DM(Medical Oncology)(Adyar,Chennai), ECMO, MRCP SCE(UK)

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Dr. Owais Mohammed
Medical Oncologist

Dr. Owais Mohammed

MBBS, MD (General Medicine), DrNB (Medical Oncology), ECMO, MRCP SCE (Medical Oncology) (UK)

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Dr. T. Raghavender Reddy
Medical Oncologist

Dr. T. Raghavender Reddy

MBBS, DM (Medical Oncology), MD (Radiation Oncology)

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Dr. N. Kiranmayee
Medical Oncologist

Dr. N. Kiranmayee

MBBS, DM (Medical Oncology), MD (Internal Medicine)

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Dr. Muralidhar Muddusetty
Surgical Oncologist

Dr. Muralidhar Muddusetty

MBBS (AIIMS), MS (Surgery) (AIIMS), DNB (Surgical Oncology), MRCS (Edinburgh)

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Dr. Raghavendra Naik
Surgical Oncologist

Dr. Raghavendra Naik

MBBS, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Mohammed  Imaduddin
Surgical Oncologist

Dr. Mohammed Imaduddin

M.B.B.S, MS (General Surgery), M.Ch (Surgical Oncology)

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Dr. Vinay Mamidala
Surgical Oncologist

Dr. Vinay Mamidala

MBBS, MS(General Surgery), M.Ch(Surgical Oncology), FMAS, FARIS(Ongoing)

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Dr. Paila Gowri Naidu
Surgical Oncologist

Dr. Paila Gowri Naidu

MBBS, MS (General Surgery), M.Ch (Surgical Oncology), FMAS

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Dr. Venkata Sushma P
Radiation Oncologist

Dr. Venkata Sushma P

MBBS, MD (Radiation Oncology)

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Dr. Kirti Ranjan Mohanty
Radiation Oncologist

Dr. Kirti Ranjan Mohanty

MBBS, MD (Radiation Oncology)

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Dr. Gangadhar Vajrala
Radiation Oncologist

Dr. Gangadhar Vajrala

MBBS, MD (Radiation Oncology), MPH

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Dr. Basudev Pokhrel
Hematologist

Dr. Basudev Pokhrel

MBBS, M.D (Immunohematology & Blood Transfusion)

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Dr. Mohammed Imran
Interventional Radiologist

Dr. Mohammed Imran

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Dr. Vajja Sandeep Kumar
Surgical Oncologist

Dr. Vajja Sandeep Kumar

MBBS, MS (General Surgery), DrNB (Surgical Oncology), FALS Oncology

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Dr. Sridhar Kamani
Surgical Oncologist

Dr. Sridhar Kamani

MBBS, MS (General Surgery), DrNB (Surgical Oncology)

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Regional Picture

Lung Cancer in Telangana & Andhra Pradesh

Lung cancer is the leading cause of cancer death in men across Telangana and Andhra Pradesh, and a rapidly rising cancer in women — including women who have never smoked. Several regional realities matter. Tobacco use in all forms — bidis, cigarettes, hookah, chillum — remains very common in men and is the dominant cause of male lung cancer. Indoor air pollution from biomass cooking fuels in rural areas, second-hand smoke in homes, and outdoor air pollution in Hyderabad and the Vizag industrial belt all contribute, particularly to the rise in non-smoking women.

A particular Indian and East Asian pattern stands out: a substantial proportion of lung adenocarcinomas in non-smoking women carry targetable mutations such as EGFR or ALK, which respond very well to oral targeted therapy. This makes molecular testing essential for every patient — and means that a never-smoker with a persistent cough or unexplained breathlessness deserves a chest X-ray and specialist evaluation, not reassurance based on smoking history alone.

Causes & Risk Factors

Common Causes & Risk Factors

Lung cancer has multiple causes — and a growing share of cases now occur in people who have never smoked. Risk factors group into four broad categories.

Tobacco & smoke

  • Smoking — bidis, cigarettes, hookah, chillum (the strongest single risk factor)
  • Second-hand smoke exposure at home or work

Air pollution

  • Indoor air pollution from biomass cooking fuels (wood, coal, dung)
  • Outdoor air pollution, particularly fine particulate matter (PM 2.5)

Occupational & environmental

  • Asbestos, silica, diesel exhaust, arsenic, chromium and certain industrial chemicals
  • Exposure to radon gas in some homes and underground workplaces
  • Previous radiation therapy to the chest

Medical & genetic

  • Chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis
  • A personal or family history of lung cancer
  • HIV infection
  • Age above 50 (most lung cancers occur in this age group, though younger cases are increasingly seen)
DNA

Molecular testing changes everything for lung cancer

Lung adenocarcinomas in Indian women often carry EGFR or ALK mutations that respond to oral targeted therapy — sometimes controlling advanced cancer for years. Comprehensive molecular and immunohistochemistry testing is now standard at diagnosis for every patient at CION.

When to Act

When to See a Lung Cancer Specialist

Any of the following should prompt a chest X-ray or low-dose CT scan and specialist evaluation:

  • A persistent cough lasting more than 3 weeks, or any change in a chronic cough
  • Coughing up blood or blood-stained sputum, even once
  • Persistent chest pain or shortness of breath
  • Recurrent chest infections in the same part of the lung
  • Hoarseness of voice lasting more than 2–3 weeks
  • Unexplained weight loss, persistent fatigue, or loss of appetite
  • An abnormal shadow or nodule found on a chest X-ray or CT scan
  • A persistent cough in a never-smoker — particularly an Indian woman over 40 — that does not respond to standard treatment
  • A long history of smoking or significant occupational dust/chemical exposure with any new respiratory symptom

A short specialist consultation and the right diagnostic test — imaging, endoscopy, biopsy, or blood test as appropriate — is usually enough to confirm or rule out cancer. Early action is always easier than catching up later.

A cough that won't settle, blood-streaked sputum, or an unexpected lung nodule on a scan? Book a free consultation at your nearest CION Cancer Clinic.

Get Expert Care

Specialist Lung Cancer Care at CION Cancer Clinics

Our NABH-accredited centres across Hyderabad deliver evidence-based lung cancer care — from CT and PET-CT staging, bronchoscopy and EBUS-guided biopsy through to comprehensive molecular and immunohistochemistry testing, minimally invasive VATS and robotic lung surgery, advanced radiation therapy (IMRT/IGRT/SBRT), modern targeted therapy (EGFR, ALK, ROS1, BRAF, KRAS, MET inhibitors), and immunotherapy combinations for advanced disease — guided by NCCN and ESMO protocols and reviewed for every patient by a multidisciplinary thoracic-oncology tumour board.

For a detailed walk-through of lung cancer diagnosis, treatment options, costs, and our specialist team, see our dedicated page on lung cancer treatment in Hyderabad.

Medical Disclaimer: This page is intended for general informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified oncologist for guidance specific to your medical condition. Content on this page is periodically reviewed and updated by CION's medical team in accordance with current clinical guidelines.
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